Innovative technologies to enable your research.
State-of-the-art technologies allow us to arrive faster to better solutions. Chiral technologies, flow chemistry, synthesis of linkers and labels and PROTAC are some of Syncom’s specialties.
Chirality is a core expertise in Syncom. We are well-known experts in classical resolution and the inventors of the “Dutch resolution”. Our diastereomeric salt screening system allows for a rapid screening of resolving agents (over 300 available in-house), with a success rate of >95%. The same system can be applied to salt formation screening for purification purposes. Syncom is directly involved in new developments in the field of chirality, such as attrition enhanced deracemization and Buoyant density separation.
Continuous flow technologies enable us to push the limits of organic synthesis. Highly reactive intermediates, exothermic or multiphasic reactions and photochemistry are some examples of reactions that greatly benefit from the use of continuous reactors.
At the interface with biology, Syncom actively works on the design and synthesis of linkers and labels (fluorescence, near IR or cytotoxic drugs). At MercachemSyncom, we have developed a toolbox for proteolysis targeting chimeras (PROTAC).